Clinical Research Directory

Inclusion Criteria: * Onset of symptoms for uncontrolled passage of fecal material for at least 6 months prior to enrollment. * At least 2-4 staining, solid or liquid FI episodes in the 4 weeks prior to enrollment * Documented normal colonoscopy in the last 3 years * Normal sigmoidoscopy as part of screening * Signed consent Exclusion Criteria: * Pregnant or breastfeeding women * Rectal prolapse grade ≥ III * Hemorrhoids Grade ≥ II. * Obstetrical injuries including third- and fourth-degree tears in the anal sphincter within the past 6 months * Internal anal sphincter separation \>270 degrees on Transrectal Ultrasound (TRUS). * Congenital malformation of anus or rectum * History of pelvic surgery in the past 6 months. * inflammatory bowel disease. * Presence of Intestinal stoma * History of pelvic radiation within the previous 12 months or presence of active radiation proctitis. * Presence of existing implant in the anal or rectal region. * Active anal or rectal conditions in the last 6 months * Abnormal blood coagulation * Patients currently receiving immunotherapy or chemotherapy.