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ENROLLING BY INVITATION
NCT07436689
PHASE3

Long-Term Open-Label Extension Study of Oral Levosimendan

Sponsor: Tenax Therapeutics, Inc.

View on ClinicalTrials.gov

Summary

The purpose of this study is to provide continued access to treatment with oral levosimendan (TNX-103) and to describe the safety of continued use of TNX-103 in participants with pulmonary hypertension with heart failure with preserved left ventricular ejection fraction (PH-HFpEF) who received TNX-103 in a parent study.

Official title: A Multicenter, Open-Label, Long-Term Extension Study for Oral Levosimendan (TNX-103)

Key Details

Gender

All

Age Range

Any - Any

Study Type

INTERVENTIONAL

Enrollment

800

Start Date

2026-03-13

Completion Date

2029-03

Last Updated

2026-03-19

Healthy Volunteers

No

Interventions

DRUG

TNX-103

Open-label oral levosimendan 1-3mg

Locations (5)

Tenax Investigational Site

Chicago, Illinois, United States

Tenax Investigational Site

Minneapolis, Minnesota, United States

Tenax Investigational Site

Rochester, Minnesota, United States

Tenax Investigational Site

St Louis, Missouri, United States

Tenax Investigational Site

Charleston, South Carolina, United States