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NOT YET RECRUITING
NCT07437339
PHASE4

Volume Reduction for Open Fracture Irrigation

Sponsor: Inova Health Care Services

View on ClinicalTrials.gov

Summary

The purpose of this study is to help doctors who treat open fractures understand how much fluid is required when cleaning out the wound. Participants will spend about 12 months in this study and will be asked to answer study questions about your recovery at your typical follow up clinic visits with your surgeon. After the surgeon has determined a participant's bone has healed, any remaining study visits can be conducted over the phone, email, and/or mail. Participants will not be asked to attend additional clinic visits as part of this study. Researchers will compare two different fluid volume protocols to determine if one results in better fracture and/or wound healing.

Official title: Volume Reduction for Open Fracture Irrigation: A Randomized Prospective Feasibility Trial

Key Details

Gender

All

Age Range

18 Years - Any

Study Type

INTERVENTIONAL

Enrollment

200

Start Date

2026-02-27

Completion Date

2027-12-31

Last Updated

2026-03-24

Healthy Volunteers

No

Conditions

Interventions

DRUG

0.9% Sodium Chloride

Sterile 0.9% sodium chloride irrigation administered intraoperatively for the purposes of irrigating open fracture wounds. The volume of sterile 0.9% sodium chloride solution used during irrigation is determine by the arm participants are randomized to and the open fracture classification as determined by the study surgeon in the operating room.

Locations (1)

Inova Health System

Falls Church, Virginia, United States