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Evaluation of Food Additive Contributions to Obesity: Pilot Study 1
Sponsor: McMaster University
Summary
The effects of food additives on body weight in humans are largely unknown. This is a pilot cross-over double blind RCT in obese adults aimed to test the feasibility of measuring food consumption over 24 hours after one-time administration of K sorbate versus placebo after participants reduce the background consumption of related food additives.
Key Details
Gender
All
Age Range
20 Years - 80 Years
Study Type
INTERVENTIONAL
Enrollment
20
Start Date
2026-02-10
Completion Date
2026-06
Last Updated
2026-02-27
Healthy Volunteers
No
Conditions
Interventions
Potassium sorbate one-time administration followed by washout then placebo one-time administration
K sorbate 450 mg will be administered with breakfast during testing session 1, followed by a minimum of 2-week washout and then placebo administration with breakfast during testing session 2
Placebo one-time administration followed by washout then potassium sorbate one-time administration
Placebo will be administered with breakfast during testing session 1, followed by a minimum of 2-week washout and then K sorbate 450 mg administration with breakfast during testing session 2
Locations (1)
McMaster University Medical Centre
Hamilton, Ontario, Canada