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Topical GHK-Cu Gel for Acute Skin Wound Healing
Sponsor: Hudson Biotech
Summary
This study will evaluate whether a topical gel containing GHK-Cu (a copper(II)-peptide complex) can safely speed up healing of small, standardized skin wounds in healthy adults compared with a matching vehicle gel. Participants will receive two small punch-biopsy wounds on the upper arm; each wound will be randomly assigned to receive GHK-Cu gel or vehicle gel under identical dressings. Wounds will be photographed and assessed over 3 weeks, with a follow-up visit to evaluate scar quality.
Official title: A Phase 2, Randomized, Double-Blind, Vehicle-Controlled, Split-Wound Study of Topical GHK-Cu (Copper(II)-Peptide Complex) Gel to Accelerate Re-Epithelialization of Standardized Acute Skin Wounds in Healthy Adults
Key Details
Gender
All
Age Range
18 Years - 55 Years
Study Type
INTERVENTIONAL
Enrollment
60
Start Date
2026-02-02
Completion Date
2028-03-17
Last Updated
2026-02-27
Healthy Volunteers
Yes
Interventions
GHK-Cu Gel (Copper(II)-peptide complex)
topical gel, 0.1% w/w; apply a thin film (approx. 0.5 g) once daily for 14 days.
vehicle Gel (placebo comparator)
ehicle Gel (placebo comparator
Locations (1)
Peking University Shenzhen Hospital
Shenzhen, Guangdong, China