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RECRUITING
NCT07437586
PHASE2

Topical GHK-Cu Gel for Acute Skin Wound Healing

Sponsor: Hudson Biotech

View on ClinicalTrials.gov

Summary

This study will evaluate whether a topical gel containing GHK-Cu (a copper(II)-peptide complex) can safely speed up healing of small, standardized skin wounds in healthy adults compared with a matching vehicle gel. Participants will receive two small punch-biopsy wounds on the upper arm; each wound will be randomly assigned to receive GHK-Cu gel or vehicle gel under identical dressings. Wounds will be photographed and assessed over 3 weeks, with a follow-up visit to evaluate scar quality.

Official title: A Phase 2, Randomized, Double-Blind, Vehicle-Controlled, Split-Wound Study of Topical GHK-Cu (Copper(II)-Peptide Complex) Gel to Accelerate Re-Epithelialization of Standardized Acute Skin Wounds in Healthy Adults

Key Details

Gender

All

Age Range

18 Years - 55 Years

Study Type

INTERVENTIONAL

Enrollment

60

Start Date

2026-02-02

Completion Date

2028-03-17

Last Updated

2026-02-27

Healthy Volunteers

Yes

Interventions

DRUG

GHK-Cu Gel (Copper(II)-peptide complex)

topical gel, 0.1% w/w; apply a thin film (approx. 0.5 g) once daily for 14 days.

DRUG

vehicle Gel (placebo comparator)

ehicle Gel (placebo comparator

Locations (1)

Peking University Shenzhen Hospital

Shenzhen, Guangdong, China