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RECRUITING
NCT07438288

Predictors of Decompensation, Acute-on-chronic Liver Failure and Mortality in Liver Cirrhosis

Sponsor: Singapore General Hospital

View on ClinicalTrials.gov

Summary

The purpose of this study is to identify factors that predict the development of decompensation, acute-on-chronic liver failure (ACLF) and death in patients with liver cirrhosis. Clinical data will be retrieved from existing hospital records. This information may help doctors to identify patients with cirrhosis who are at risk of deterioration earlier (before they develop complications) and to develop effective treatment strategies to prevent or delay these complications. This study is designed as a prospective, non-interventional, observational study. This means that if you agree to participate in the study, you will not be required to undergo any additional hospital visits, tests, procedures or interventions other than the usual standard-of-care management that your doctor will provide. If you consent to participate in this study, you will be providing the study investigators permission to review and analyse your clinical data from the hospital clinical records. Your data will be collected throughout the course of your disease until liver transplantation or death.

Official title: Predictors of Decompensation, Acute-on-chronic Liver Failure and Mortality in Liver Cirrhosis - a Multicentre, Prospective, Observational Study From the SingHealth Chronic Liver Disease Registry (SoLiDaRity-DAM)

Key Details

Gender

All

Age Range

18 Years - Any

Study Type

OBSERVATIONAL

Enrollment

2200

Start Date

2022-08-12

Completion Date

2032-08-12

Last Updated

2026-02-27

Healthy Volunteers

No

Interventions

OTHER

Observation

Patients with liver cirrhosis will be observed to monitor for death

Locations (3)

Changi General Hospital

Singapore, Singapore

Sengkang General Hospital

Singapore, Singapore

Singapore General Hospital

Singapore, Singapore