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NCT07438769

Ultrasound Predictors of Persistent Burn Scar Pain After Blast and Drone-Related Injuries: A Prospective Cohort Study

Sponsor: Ukrainian Society of Regional Anesthesia and Pain Therapy

View on ClinicalTrials.gov

Summary

Persistent burn scar pain is common after blast and drone-related injuries and may be driven by scar fibrosis, vascular activity, and peripheral nerve involvement within scar tissue. This prospective cohort study aims to determine whether early ultrasound features of scars and nerves predict persistent clinically significant scar pain at 3 and 6 months. Ultrasound measures include scar thickness, echogenicity, Power Doppler vascularity, dynamic adhesion (gliding) assessment, and ultrasound signs of nerve involvement ("US-nerve positive"). Clinical outcomes include pain intensity (NRS), neuropathic pain screening (DN4), and functional interference.

Key Details

Gender

All

Age Range

18 Years - 60 Years

Study Type

OBSERVATIONAL

Enrollment

150

Start Date

2026-03-24

Completion Date

2026-05-23

Last Updated

2026-02-27

Healthy Volunteers

No

Locations (1)

Vinnitsya Regional Clinical Hospital n.a Pirogov

Vinnitsya, Select, Ukraine