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RECRUITING
NCT07439744
NA

NUTRIMOOD-Inflammation and Depressive Comorbidity in Obesity: Modulation by Omega-3 Polyunsaturated Fatty Acids Status

Sponsor: National Science and Technology Council, Taiwan

View on ClinicalTrials.gov

Summary

A 12-week, randomized, placebo-controlled trial testing the efficacy of n-3 PUFA treatment (EPA, 2 g/day) in alleviating depressive symptoms in a subgroup of obese subjects with comorbid depression and low n-3 PUFA status (n-3 index \< 8%) (81), from the Taiwanese cohort. Associations with PLA2/COX2 genotypes, lifestyle, nutritional profiles and gut microbiota will also be determined.

Official title: Effects of 12-week n-3 PUFA Treatment (EPA) on Depressive Symptoms in Overweight/Obese Depressed Subjects With Low n-3 PUFA Status: Relationship With Systemic Inflammation

Key Details

Gender

All

Age Range

18 Years - 54 Years

Study Type

INTERVENTIONAL

Enrollment

50

Start Date

2025-03-01

Completion Date

2027-12

Last Updated

2026-02-27

Healthy Volunteers

No

Conditions

Interventions

DIETARY_SUPPLEMENT

Eicosapentaenoic acid (omega-3 fatty acid)

25 participants are assigned

DIETARY_SUPPLEMENT

Placebo

25 participants are assigned

Locations (1)

Mind Body Interface Research Center (MBI Lab & Care)

Taichung, Taichung, Taiwan