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RECRUITING
NCT07439796
PHASE1

A Study of ORN252 in Healthy Participants

Sponsor: Orna Therapeutics, Inc.

View on ClinicalTrials.gov

Summary

The purpose of this study is to assess the safety and tolerability of ORN252 in healthy adult participants.

Official title: A Phase 1 Study to Investigate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of ORN252 in Healthy Participants

Key Details

Gender

All

Age Range

18 Years - 55 Years

Study Type

INTERVENTIONAL

Enrollment

20

Start Date

2026-03

Completion Date

2027-03

Last Updated

2026-03-19

Healthy Volunteers

Yes

Interventions

BIOLOGICAL

ORN252

ORN252 is a lipid nanoparticle encapsulating a circular RNA encoding an anti-CD19 CAR protein.

Locations (1)

Nucleus Network

Herston, Queensland, Australia