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AGECTO Study: PCI vs. Optimal Medical Therapy for CTO in the Octogenarian Patients
Sponsor: San Luigi Gonzaga Hospital
Summary
The study compares an interventional strategy (PCI) with optimal medical therapy (OMT) in ultra-octogenarians with chronic total occlusions (CTO). Results suggest that successful PCI leads to significant improvements in symptoms and quality of life compared to OMT alone. While initially carrying higher procedural risks, CTO-PCI is considered feasible and safe in experienced centers. There is also potential for long-term benefits in survival and a reduction in major adverse cardiovascular events (MACE). The choice between treatments depends on an individual risk-benefit assessment, considering the patient's overall condition.
Official title: AGECTO Study: A Comparative Study of Percutaneous Coronary Intervention vs. Medical Therapy for Chronic Total Occlusion in Octogenarian Patients
Key Details
Gender
All
Age Range
Any - Any
Study Type
OBSERVATIONAL
Enrollment
200
Start Date
2025-07-01
Completion Date
2026-12-01
Last Updated
2026-03-02
Healthy Volunteers
Yes
Conditions
Locations (1)
Rivoli Hospital
Rivoli, Italy