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RECRUITING
NCT07442656

Frailty and Outcomes in Older Emergency Department Patients With Pneumonia

Sponsor: Ege University

View on ClinicalTrials.gov

Summary

Pneumonia is one of the leading causes of infection-related mortality in the older population. Traditional severity scores used in emergency departments, such as the Pneumonia Severity Index (PSI) and CURB-65, primarily focus on acute physiological derangements and may not adequately capture biological reserve and frailty in older adults. Frailty is a geriatric syndrome reflecting increased vulnerability to stressors and reduced recovery capacity. This prospective observational cohort study aims to evaluate the predictive value of the Clinical Frailty Scale (CFS) for in-hospital mortality, 30-day mortality, and morbidity in patients aged 65 years and older presenting to the emergency department with pneumonia. Additionally, the study will assess whether incorporating frailty assessment into existing pneumonia severity scores improves prognostic accuracy.

Official title: Impact of Clinical Frailty Scale on Morbidity and Mortality in Older Adults Diagnosed With Pneumonia in the Emergency Department: A Prospective Observational Cohort Study

Key Details

Gender

All

Age Range

65 Years - Any

Study Type

OBSERVATIONAL

Enrollment

150

Start Date

2026-01-01

Completion Date

2026-04-30

Last Updated

2026-03-02

Healthy Volunteers

No

Interventions

OTHER

Clinical frailty scale

Frailty assessment performed at emergency department presentation using the 9-point Clinical Frailty Scale.

DIAGNOSTIC_TEST

Clinical Frailty Scale (CFS)

The Clinical Frailty Scale (CFS) will be assessed on a 1-9 scale. The CFS score obtained at presentation will also be compared with the patient's baseline CFS prior to the onset of the current illness symptoms.

Locations (1)

Özge Can

Izmir, Bornova, Turkey (Türkiye)