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NCT07443176

FCI-Glioblastoma Study

Sponsor: University of Aberdeen

View on ClinicalTrials.gov

Summary

The goal of this study is to test if a new type of MRI scanner, called Field-Cycling Imaging (FCI), can tell the difference between tumour growth (progression) and 'pseudo-progression' (which looks like tumour but is not cancerous tissue) in patients with glioblastoma. The main question it aims to answer is: • Can FCI differentiate glioblastoma progression from pseudo-progression? Participants will undergo a standard MRI scan and an FCI scan, three times during the study. One before starting adjuvant chemotherapy, another one after three cycles and one at the end of treatment.

Official title: Applying New MRI Technology to Improve Outcomes From Chemoradiotherapy Treatment for Adult Patients With Glioblastoma

Key Details

Gender

All

Age Range

18 Years - 70 Years

Study Type

OBSERVATIONAL

Enrollment

18

Start Date

2026-02

Completion Date

2027-12

Last Updated

2026-03-02

Healthy Volunteers

No

Interventions

OTHER

Baseline Field-Cycling Imaging research scan

FCI scan at baseline

OTHER

Baseline 3T MRI research scan

MRI scan at baseline

OTHER

Second Field-Cycling Imaging research scan

FCI scan after three cycles of chemotherapy

OTHER

Second 3T MRI research scan

MRI scan after three cycles of chemotherapy

OTHER

Final Field-Cycling Imaging research scan

FCI scan at the end of chemotherapy

OTHER

Final 3T MRI research scan

MRI scan at the end of chemotherapy

Locations (1)

University of Aberdeen

Aberdeen, United Kingdom