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RECRUITING
NCT07443891
NA

Brain Network Changes After Vibro-tactile Stimulation in Laryngeal Dystonia

Sponsor: University of Minnesota

View on ClinicalTrials.gov

Summary

Laryngeal dystonia (LD) is a focal dystonia affecting laryngeal muscles, causing involuntary spasms that impair speech production. Recent research demonstrated that non-invasive vibrotactile stimulation (VTS) of the laryngeal area can provide acute symptom relief in up to 57% of patients, with improvements in voice quality and reductions in perceived speech effort lasting from minutes to several days. However, the neural mechanisms underlying this therapeutic effect and the factors determining individual treatment response remain incompletely understood. The objective is to evaluate the acute effects of VTS on voice and speech parameters in participants with LD while characterizing associated changes in brain resting-state networks using magnetic resonance imaging (MRI).

Official title: Functional Neural Network Changes After Vibro-tactile Stimulation in Laryngeal Dystonia

Key Details

Gender

All

Age Range

18 Years - 75 Years

Study Type

INTERVENTIONAL

Enrollment

20

Start Date

2026-01-14

Completion Date

2027-02-28

Last Updated

2026-03-19

Healthy Volunteers

Yes

Interventions

DEVICE

Vibrotactile Stimulation (VTS)

Applied to the laryngeal area using a non-invasive vibrating device.

Locations (1)

University of Minnesota

Minneapolis, Minnesota, United States