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Upper Airway Ultrasound to Predict Difficult Laryngoscopy in Neonates and Infants
Sponsor: Children's Hospital of Philadelphia
Summary
Upper airway ultrasound (UA-US) has been utilized in adults to predict difficult laryngoscopy (Cormick-Lehane view 3 or 4) and difficult tracheal intubation (DTI) (≥3 intubation attempts) and with moderate-to-high sensitivity and specificity. This bedside technique is reproducible, easy-to-do without any additional radiation risk, and was added to the most recent American Society of Anesthesiologists (ASA) Practice Guidelines for Difficult Airway Management in Adults. However, UA-US has only been applied to older children ages 5-12 and has not been examined in neonates and infants. Thus, the aim of this observational study using UA-US to predict difficult laryngoscopy and tracheal intubation in neonates and infants presenting for diagnostic, procedural or surgical care under general anesthesia requiring endotracheal intubation.
Official title: Upper Airway Ultrasound to Predict Difficult Airway Management in Neonates and Infants: A Prospective Observational Study
Key Details
Gender
All
Age Range
Any - 365 Days
Study Type
OBSERVATIONAL
Enrollment
180
Start Date
2026-03-02
Completion Date
2027-12-31
Last Updated
2026-03-04
Healthy Volunteers
Yes
Interventions
Upper airway ultrasound
The investigator will perform 6 UA-US measurements will be obtained with a high frequency linear array or curvilinear US probe following induction of anesthesia but prior to laryngoscopy or TI: distance from the skin to the epiglottis, distance from the skin to the hyoid bone, distance from skin to vocal cords, hyomental distance, tongue thickness, and tongue cross-sectional area.
Locations (1)
Children's Hospital of Philadelphia
Philadelphia, Pennsylvania, United States