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MRI-Based Prediction of Dienogest Response in Endometriosis
Sponsor: Chungnam National University Sejong Hospital
Summary
The goal of this prospective observational study is to learn whether magnetic resonance imaging (MRI) findings can help predict treatment response to dienogest in women with endometriosis. Endometriosis is a common gynecologic condition that can cause chronic pelvic pain and negatively affect quality of life. Although dienogest is widely used as a standard medical treatment, individual responses to treatment vary. The main questions this study aims to answer are: * Whether baseline MRI characteristics of endometriotic lesions are associated with improvement in pelvic pain after dienogest treatment. * Whether MRI findings can help identify patients who are more likely to benefit from dienogest therapy. Participants diagnosed with endometriosis who are prescribed dienogest as part of their routine clinical care will be enrolled. This study does not assign any investigational intervention. Participants will undergo standard clinical follow-up, including pelvic pain assessment using visual analog scale (VAS) scores, quality of life questionnaires, and routine MRI examinations. Clinical and imaging data will be collected prospectively and analyzed to explore imaging predictors of treatment response.
Official title: Predicting the Efficacy of Dienogest in Patients With Endometriosis Using MRI
Key Details
Gender
FEMALE
Age Range
19 Years - 45 Years
Study Type
OBSERVATIONAL
Enrollment
48
Start Date
2025-10-14
Completion Date
2027-03
Last Updated
2026-03-03
Healthy Volunteers
No
Conditions
Locations (1)
Sejong Chungnam National University Hospital
Sejong, Sejong Special Self-Governing City, South Korea