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RECRUITING
NCT07446608

MRI-Based Prediction of Dienogest Response in Endometriosis

Sponsor: Chungnam National University Sejong Hospital

View on ClinicalTrials.gov

Summary

The goal of this prospective observational study is to learn whether magnetic resonance imaging (MRI) findings can help predict treatment response to dienogest in women with endometriosis. Endometriosis is a common gynecologic condition that can cause chronic pelvic pain and negatively affect quality of life. Although dienogest is widely used as a standard medical treatment, individual responses to treatment vary. The main questions this study aims to answer are: * Whether baseline MRI characteristics of endometriotic lesions are associated with improvement in pelvic pain after dienogest treatment. * Whether MRI findings can help identify patients who are more likely to benefit from dienogest therapy. Participants diagnosed with endometriosis who are prescribed dienogest as part of their routine clinical care will be enrolled. This study does not assign any investigational intervention. Participants will undergo standard clinical follow-up, including pelvic pain assessment using visual analog scale (VAS) scores, quality of life questionnaires, and routine MRI examinations. Clinical and imaging data will be collected prospectively and analyzed to explore imaging predictors of treatment response.

Official title: Predicting the Efficacy of Dienogest in Patients With Endometriosis Using MRI

Key Details

Gender

FEMALE

Age Range

19 Years - 45 Years

Study Type

OBSERVATIONAL

Enrollment

48

Start Date

2025-10-14

Completion Date

2027-03

Last Updated

2026-03-03

Healthy Volunteers

No

Locations (1)

Sejong Chungnam National University Hospital

Sejong, Sejong Special Self-Governing City, South Korea