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Vascular Intervention Strategies Trial for Alzheimer's
Sponsor: University of Southern California
Summary
The proposed pharmacist-led study is a feasibility pilot trial for the management of vascular risk factors of hypertension and hypercholesterolemia in 10 APOE ε4 carriers, 50-75, at-risk for dementia. All participants will receive angiotensin receptor blockers (ARBs) for high blood pressure, and hydrophilic statins (or a non-statin alternative) for high cholesterol over a six-month period.
Official title: Vascular Intervention Strategies Trial for Alzheimer's (VISTA)
Key Details
Gender
All
Age Range
50 Years - 75 Years
Study Type
INTERVENTIONAL
Enrollment
10
Start Date
2026-03
Completion Date
2028-06
Last Updated
2026-03-05
Healthy Volunteers
No
Interventions
Angiotensin Receptor Blockers (ARBs)
Participants receive pharmacist-led management of vascular risk factors over a six-month period. This includes blood pressure management with angiotensin receptor blockers (ARBs).
Hydrophilic Statins or Non-Statin Alternative
Participants receive pharmacist-led management of vascular risk factors over a six-month period. This includes cholesterol management with hydrophilic statins or a non-statin alternative if statins are not appropriate.
Locations (1)
Clinical Sciences Building (CSC)
Los Angeles, California, United States