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Effect of Striatal Temporal Interference Stimulation on Language Processing in Neurodegenerative Diseases
Sponsor: Masaryk University
Summary
The purpose of this study is to investigate the immediate effects of non-invasive temporal interference stimulation (TIS) targeting the striatum on sentence processing and brain connectivity in patients with neurodegenerative diseases.
Official title: Immediate Effects of Non-invasive Temporal Interference Stimulation Targeting Deep Fronto-Striatal Structures on Language Processing and Behavioral Performance in Patients With Neurodegenerative Diseases
Key Details
Gender
All
Age Range
60 Years - 80 Years
Study Type
INTERVENTIONAL
Enrollment
70
Start Date
2026-03
Completion Date
2028-12
Last Updated
2026-03-04
Healthy Volunteers
No
Conditions
Interventions
Active Temporal Interference Stimulation (TIS)
Non-invasive brain interference stimulation applied for approximately 20 minutes while the participant performs a sentence comprehension task.
Placebo / Sham TIS
Placebo stimulation applied for approximately 20 minutes while the participant performs a sentence comprehension task.
Locations (1)
CEITEC MU (Central European Institute of Technology, Masaryk University)
Brno, South Moravian, Czechia