Clinical Research Directory

Inclusion Criteria: * Age is 18 years or older * Admitted to the ICU for an expected duration ≥ 24 hours from enrollment * Have at least one of the following conditions: Acute Sepsis or Septic Shock Admitted to the ICU following elective cardiothoracic surgery Acute respiratory failure requiring non-invasive ventilation or high-flow nasal cannula (HFNC) oxygenation Shock requiring vasopressor therapy Mechanically ventilated - Current RASS ≥ -3 and not expected to require deep sedation (RASS \< -3) during the ICU stay Exclusion Criteria: \- Any structural abnormality or head condition, including the presence of a device, that would prevent the use of the Ceribell EEG system for the entire anticipated EEG monitoring period. Examples include: Craniectomy with a missing bone flap in a region where Ceribell EEG electrodes would be placed. Anticipated use of continuous EEG for a purpose other than delirium detection during the entire expected monitoring period. * Baseline neurological dysfunction (Glasgow Coma Scale \< 10) and pre-existing brain injuries such as stroke with known deficits, severe TBI * History of moderate-severe dementia (IQCODE ≥ 3.5) * APACHE II score \> 30, or SOFA \> 9 at enrollment