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NOT YET RECRUITING
NCT07450755
NA

Concomitant PFA Bsaed PVI Plus LAAC

Sponsor: Asklepios proresearch

View on ClinicalTrials.gov

Summary

A multicenter, prospective registry of concomitant Farapulse (Boston scientific) based PVI and Watchman Flx device (Boston scientific) based LAAC procedures was planned in order to assess the acute and mid-time safety, efficacy and efficiency of this approach (COCONUT II study). If available the transseptal puncture will be performed by the VersaCross System (Boston scientific). If already available LAAC procedure will be performed utilizing the Watchman Flx pro device (Boston scientific) or the Watchman Flx device (Boston scientific). For procedure planning, assessment of the LAA size and selection of the Watchman Flx device a preprocedural cardiac computed tomography in combination with the TruePLan Software is recommended.

Official title: Pulse Field Ablation Based Pulmonary Vein Isolation Concomitant With Left Atrial Appendage Closure - The COCONUT II Study

Key Details

Gender

All

Age Range

18 Years - Any

Study Type

INTERVENTIONAL

Enrollment

150

Start Date

2026-03-01

Completion Date

2027-12-31

Last Updated

2026-03-12

Healthy Volunteers

No

Interventions

PROCEDURE

Interventional LAA Closure

LAA Closure to prevent stroke and bleeding

PROCEDURE

Pulmonary vein isolation

Pulmonary vein isolation for atrial firbrillation treatment