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NOT YET RECRUITING
NCT07453823
NA

The Effect of a Synbiotic on Intestinal Barrier Function and Microbiota Modulation in Middle-aged to Elderly Individuals With Excessive Body Weight

Sponsor: Chr Hansen - part of Novonesis

View on ClinicalTrials.gov

Summary

The study is a single-center, randomized, double-blind, placebo-controlled study in middle-aged to elderly adults with excessive body weight. The study includes an 8-week intervention period followed by a 2-week follow-up period. The study will evaluate the effect of a synbiotic consisting of two probiotic strains and a prebiotic. The aim is to investigate the effect of the synbiotic on modulating the gut microbiota and improving markers of gastrointestinal permeability and integrity and gastrointestinal discomfort.

Official title: The Effect of a Synbiotic on Intestinal Barrier Function and Microbiota Modulation in Middle-aged to Elderly Individuals With Excessive Body Weight: a Randomized, Double-blind, Placebo-controlled Study

Key Details

Gender

All

Age Range

50 Years - 70 Years

Study Type

INTERVENTIONAL

Enrollment

90

Start Date

2026-03

Completion Date

2026-12

Last Updated

2026-03-06

Healthy Volunteers

Yes

Interventions

DIETARY_SUPPLEMENT

Synbiotic

Synbiotic \- Given daily for 56 days

DIETARY_SUPPLEMENT

Placebo

Placebo \- Given daily for 56 days

Locations (1)

Atlantia Clinical Trials Ltd

Cork, Blackpool, Ireland