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ACTIVE NOT RECRUITING
NCT07455604
PHASE2

Preventing Early Childhood Caries With a Silver Diamine Fluoride Gel

Sponsor: The University of Hong Kong

View on ClinicalTrials.gov

Summary

The objective is to compare the efficacy of SDF gel with that of NaF varnish in preventing carious lesions in preschool children when applied at half-yearly intervals over a 24-month period.

Official title: Randomized Clinical Trial to Prevent Early Childhood Caries With a Silver Diamine Fluoride Gel

Key Details

Gender

All

Age Range

3 Years - 5 Years

Study Type

INTERVENTIONAL

Enrollment

1500

Start Date

2026-01-01

Completion Date

2028-12-31

Last Updated

2026-03-06

Healthy Volunteers

Yes

Interventions

DRUG

Silver diamine fluoride gel

Application of 38% SDF gel every 6 months over 24 months

DRUG

Sodium Fluoride varnish

Application of 5% NaF varnish every 6 months over 24 months

Locations (1)

The University of Hong Kong

Hong Kong, China