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RECRUITING
NCT07457736
EARLY_PHASE1
Evaluation of [18F]GATT-44 for Positron Emission Tomography Imaging of the GABA Transporter-1
Sponsor: Yale University
View on ClinicalTrials.gov
Summary
Evaluate \[18F\]GATT-44 (aka \[18F\]GAT44), to characterize its pharmacokinetic, metabolic, and in vivo binding profile, and assess the reproducibility of kinetic and binding parameters. Assess specific binding levels of \[18F\]GATT-44 by conducting a test-block study in humans. Estimate human dosimetry of \[18F\]GATT-44 by performing whole-body imaging studies.
Key Details
Gender
All
Age Range
18 Years - 60 Years
Study Type
INTERVENTIONAL
Enrollment
32
Start Date
2026-04
Completion Date
2030-01
Last Updated
2026-04-06
Healthy Volunteers
Yes
Conditions
Interventions
DRUG
[ 18F]GATT-44
First in human radiotracer being evaluated in this study.
Locations (1)
Yale University PET Center
New Haven, Connecticut, United States