Clinical Research Directory
Browse clinical research sites, groups, and studies.
International Multi-center Profile of Emergency Large-Bowel Obstruction Management and Outcomes
Sponsor: European Society for Trauma and Emergency Surgery
Summary
Mechanical large-bowel obstruction is a common and high-risk emergency surgical condition with substantial variation in diagnostic evaluation, operative timing, and management strategies across institutions and healthcare systems. Evidence guiding optimal management remains limited and is largely derived from retrospective or single-center studies. IMPEL is an international, multicenter, time-bound, prospective observational cohort study designed to characterize real-world presentation, diagnostic pathways, operative and non-operative management, and short-term outcomes in adults presenting with mechanical large-bowel obstruction. By capturing standardized patient-level, radiologic, operative, and outcome data across diverse acute care settings, IMPEL aims to describe contemporary practice patterns, quantify variation in care, and identify factors associated with morbidity, mortality, and stoma-related outcomes.
Official title: International Multi-center Profile of Emergency Large-Bowel Obstruction Management and Outcomes (IMPEL)
Key Details
Gender
All
Age Range
18 Years - Any
Study Type
OBSERVATIONAL
Enrollment
500
Start Date
2026-07-01
Completion Date
2027-07-31
Last Updated
2026-03-09
Healthy Volunteers
No