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NOT YET RECRUITING
NCT07458867

International Multi-center Profile of Emergency Large-Bowel Obstruction Management and Outcomes

Sponsor: European Society for Trauma and Emergency Surgery

View on ClinicalTrials.gov

Summary

Mechanical large-bowel obstruction is a common and high-risk emergency surgical condition with substantial variation in diagnostic evaluation, operative timing, and management strategies across institutions and healthcare systems. Evidence guiding optimal management remains limited and is largely derived from retrospective or single-center studies. IMPEL is an international, multicenter, time-bound, prospective observational cohort study designed to characterize real-world presentation, diagnostic pathways, operative and non-operative management, and short-term outcomes in adults presenting with mechanical large-bowel obstruction. By capturing standardized patient-level, radiologic, operative, and outcome data across diverse acute care settings, IMPEL aims to describe contemporary practice patterns, quantify variation in care, and identify factors associated with morbidity, mortality, and stoma-related outcomes.

Official title: International Multi-center Profile of Emergency Large-Bowel Obstruction Management and Outcomes (IMPEL)

Key Details

Gender

All

Age Range

18 Years - Any

Study Type

OBSERVATIONAL

Enrollment

500

Start Date

2026-07-01

Completion Date

2027-07-31

Last Updated

2026-03-09

Healthy Volunteers

No