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NOT YET RECRUITING
NCT07460063
NA

Routine vs. Early Postpartum Depression Screening: A Pragmatic Clinical Trial

Sponsor: Massachusetts General Hospital

View on ClinicalTrials.gov

Summary

After having a baby, some women develop a condition called postpartum depression, or PPD, which can cause sadness, anxiety, and difficulty bonding with their newborn. Right now, most women aren't screened for PPD until about 6 to 8 weeks after giving birth, but this study wants to find out if checking earlier could help identify signs sooner. To test this, researchers will work with 428 women who deliver at an MGH hospital clinic and have no history of depression. Each woman will be randomly placed into one of two groups: one group will fill out a short depression questionnaire online at 2 to 3 weeks after delivery, while the other group will follow the usual process and complete the same questionnaire at their regular 6-week visit. The results will go to each woman's doctor, who will decide if any follow-up care is needed, just like they normally would. The study will follow each participant for 6 months after delivery to see whether earlier screening makes a difference.

Key Details

Gender

FEMALE

Age Range

18 Years - Any

Study Type

INTERVENTIONAL

Enrollment

428

Start Date

2026-05

Completion Date

2027-12

Last Updated

2026-03-11

Healthy Volunteers

No

Interventions

BEHAVIORAL

Early PPD Screening

Edinburgh Perinatal Depression Scale (EPDS) administered at approximately 2 weeks postpartum