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The Impact of Low Sodium Salt Substitute Use on Serum Potassium Levels Among Patients With Hypertension
Sponsor: Johns Hopkins University
Summary
The goal of this pre-post study is to assess the risk of hyperkalemia in adults with hypertension on medication in Bangladesh. The main questions it aims to answer are: Is the risk of hyperkalemia after the initiation of Low Sodium Salt Substitute (LSSS) in people on antihypertensive medication (especially RASi) large enough to be concerned about its broad use in this population? Does initiation of LSSS correct hypokalemia in people on antihypertensive medication (especially RASi) with low serum potassium levels? Participants will be asked to reduce overall salt intake and to use LSSS on every occasion where regular salt would normally be used, including as cooking salt.
Key Details
Gender
All
Age Range
18 Years - Any
Study Type
INTERVENTIONAL
Enrollment
607
Start Date
2026-04-01
Completion Date
2027-09-30
Last Updated
2026-03-10
Healthy Volunteers
No
Conditions
Interventions
Low-sodium salt substitute
The low sodium salt substitute contains 25% potassium chloride (KCl range; 20%-35%)