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NOT YET RECRUITING
NCT07461298
NA

Multimodal Intervention for Persistent Musculoskeletal Pain in Primary Care

Sponsor: Universitat Jaume I

View on ClinicalTrials.gov

Summary

This multicenter randomized controlled trial aims to evaluate the effectiveness of a multimodal intervention for the active management of persistent musculoskeletal pain in primary care. The intervention combines pain neuroscience education, therapeutic exercise, and the promotion of self-care and healthy lifestyle habits to improve health-related quality of life in adults with persistent nonspecific musculoskeletal pain lasting at least six months. A total of 146 participants aged 18 to 70 years will be recruited from five primary care centers in the Comunitat Valenciana (Spain) and randomly assigned to either the experimental group or the control group. The primary outcome is health-related quality of life measured using the SF-36 Health Survey. Secondary outcomes include pain intensity, pain catastrophizing, kinesiophobia, central sensitization, emotional symptoms, perceived social support, medication use, and lifestyle-related variables. Assessments will be conducted at baseline, post-intervention, 6 months, and 12 months follow-up.

Official title: Effectiveness of a Multimodal Intervention Based on Pain Neuroscience Education, Therapeutic Exercise and Healthy Lifestyle Promotion in Patients With Persistent Musculoskeletal Pain in Primary Care: A Multicenter Randomized Controlled Trial

Key Details

Gender

All

Age Range

18 Years - 70 Years

Study Type

INTERVENTIONAL

Enrollment

146

Start Date

2026-06

Completion Date

2028-01

Last Updated

2026-03-10

Healthy Volunteers

No

Interventions

BEHAVIORAL

Multimodal Pain Management Program

The multimodal program combines pain neuroscience education, therapeutic exercise, and the promotion of self-care and healthy lifestyle habits. Pain neuroscience education focuses on reconceptualizing pain based on contemporary neurophysiological principles. Therapeutic exercise includes supervised physical activity aimed at improving strength, mobility, and functional capacity. The self-care component addresses lifestyle factors such as physical activity, sleep hygiene, stress management, and healthy nutrition.

OTHER

Usual Primary Care

Participants in the control group will continue receiving standard primary care treatment as determined by their healthcare providers. This may include medication, medical advice, or referral to other services according to routine clinical practice.

Locations (5)

Centro de Salud Marina Española

Elda, Alicante, Spain

Centro de Salud de Villena I

Villena, Alicante, Spain

Centro de Salud Integrado de la Vall d'Uixó

Vall d'Uixó, Castellón, Spain

Centro de Salud de Alginet

Alginet, Valencia, Spain

Centro de Salud de Benifaió

Benifaió, Valencia, Spain