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NOT YET RECRUITING
NCT07461337
PHASE1/PHASE2

Bacteriophage Therapy for Staphylococcus Lugdunensis Prosthetic Joint Infection

Sponsor: University of Calgary

View on ClinicalTrials.gov

Summary

This is a single-patient, phase I/II clinical trial that aims to evaluate the potential of a bacteriophage drug product to treat and prevent the recurrence of a Staphylococcus lugdunensis prosthetic joint infection of the hip. The patient has exhausted all conventional therapies, both surgical and medical, at considerable detriment to their quality of life. The treatment involves 2 intra-articular injections of bacteriophages into the joint and surrounding area and 14 days of intravenous phage therapy. The goal is to eliminate the infection and prevent further complications, providing a potential new treatment avenue for patients with difficult-to-treat infections.

Key Details

Gender

FEMALE

Age Range

Any - Any

Study Type

INTERVENTIONAL

Enrollment

1

Start Date

2026-03

Completion Date

2027-03

Last Updated

2026-03-10

Healthy Volunteers

No

Interventions

BIOLOGICAL

Five phage anti-Staphylococcus aureus bacteriophage cocktail

Five phage anti-Staphylococcus aureus bacteriophage cocktail for targeted treatment of a Staphylococcus lugdunensis infection.

Locations (1)

Foothills Medical Centre, University of Calgary

Calgary, Canada