Clinical Research Directory

Inclusion Criteria: 1. Male or female participants aged ≥ 18 years 2. Patients with early upper gastrointestinal cancer referred for endoscopic submucosal dissection (ESD), or patients with upper gastrointestinal precancerous lesions or precancerous conditions referred for biopsy by esophagogastroduodenoscopy (EGD) 3. Participants who are willing and able to participate in this study, complete all required examinations and follow-up visits, and who have provided written informed consent Exclusion Criteria: 1. Patients who are not eligible for surgery or who refuse any abdominal surgery in case of capsule retention and endoscopic retrieval failure 2. Patients with cardiac pacemaker or other implanted electromedical devices which could interfere with magnetic resonance 3. Suspected or known intestinal stenosis or other known risk factors for capsule retention 4. Patients with dysphagia 5. Pregnancy 6. Allergy to polymeric materials, latex, simethicone, or pronase 7. Patients plan to undergo magnetic resonance imaging examination before excretion of the capsule 8. Patients with any condition that precludes compliance with the study