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Indirect Calorimetry Measurement in the Pediatric Intensive Care Unit's Smallest Patients
Sponsor: Karolinska Institutet
Summary
Indirect calorimetry is considered the reference method for measuring energy expenditure in intensive care patients. However, in infants and small children weighing less than 10 kilograms, its clinical use has historically been limited due to technical challenges related to low tidal volumes, potential increases in dead space, and measurement precision. The goal of this observational study is to evaluate the feasibility and performance of indirect calorimetry using the Q-NRG+ device in critically ill children weighing less than 10 kg who are admitted to a pediatric intensive care unit.
Official title: Indirect Calorimetry Measurement in the Paediatric Intensive Care Unit's Smallest Patients
Key Details
Gender
All
Age Range
Any - Any
Study Type
OBSERVATIONAL
Enrollment
80
Start Date
2026-04
Completion Date
2027-12
Last Updated
2026-03-10
Healthy Volunteers
No
Conditions
Interventions
Q-NRG+
The Q-NRG+ is an indirect calorimetry device used to measure resting energy expenditure in mechanically ventilated or spontaneously breathing patients. In this study, the device is connected to the ventilator circuit or used with a canopy hood to measure oxygen consumption and carbon dioxide production for calculation of energy expenditure. Measurements are performed in addition to standard clinical care and do not alter routine treatment.
Locations (1)
Pediatric Perioperative Medicine and Intensive Care Stockholm, Sweden
Stockholm, Solna, Sweden