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RECRUITING
NCT07463508
NA

Evaluation of Bile Acid Concentrations and Their Signaling as Markers of Testicular Tumorigenesis and Germ Cell Tumor Chemosensitivity

Sponsor: University Hospital, Clermont-Ferrand

View on ClinicalTrials.gov

Summary

This is a study exploring measurable markers in the blood of patients with testicular tumors. The investigators will focus on the importance of measuring and analyzing these markers for their prognostic value and predictive response to treatment.

Official title: Evaluation of Bile Acid Concentrations and Their Signaling as Markers of Testicular Tumorigenesis and Germ Cell Tumor Chemosensitivity (TG-BIL)

Key Details

Gender

MALE

Age Range

18 Years - Any

Study Type

INTERVENTIONAL

Enrollment

20

Start Date

2026-01-01

Completion Date

2029-01-01

Last Updated

2026-03-11

Healthy Volunteers

No

Interventions

BIOLOGICAL

blood sampling

Blood samples will allow the measurement of AFP, LDH and HCG as well as the measurement of testosterone, glucose, cholesterol, triglycerides and bile acids

PROCEDURE

Tissue sampling

On these tissues (tumoral and non-tumoral), the investigators will carry out analysis of the bile acid composition by mass spectrometry, molecular characterization by RNAseq, histological characterization and analysis in cell culture

Locations (1)

CHU Clermont-Ferrand

Clermont-Ferrand, France