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Postoperative High-flow Nasal Oxygenation After High-risk Surgery in the Frail Adult
Sponsor: Region Stockholm
Summary
High flow nasal oxygen (HFNO) in the immediate postoperative period has been demonstrated to reduce the risk of postoperative pulmonary complications (PPC) after cardiothoracic surgery. In specific groups of patients such as the obese and after upper abdominal surgery the results are contradictive. However, there is lack of evidence if HFNO in the general high-risk patient after abdominal and non-cardiac thoracic surgery can reduce the prevalence of PPC, hypoxaemia and escalation of therapy. Therefore, the investigators aim to compare the use of HFNO with conventional oxygen therapy (COT) in high-risk patients after abdominal and non-cardiac thoracic surgery regarding postoperative pulmonary complications.
Key Details
Gender
All
Age Range
18 Years - Any
Study Type
INTERVENTIONAL
Enrollment
200
Start Date
2026-03-09
Completion Date
2029-03-09
Last Updated
2026-03-11
Healthy Volunteers
No
Interventions
High Flow Oxygen
High flow nasal oxygen will be administered in the intervention group
Oxygen
Oxygen delivered by nasal cannula or oxymask
Locations (1)
Karolinska University Hospital
Stockholm, Sweden