Clinical Research Directory

Inclusion Criteria: * Adults aged 18 years or older * Mechanical ventilation for more than 3 days * Total ICU length of stay greater than 7 days * Classified as "High Risk" using a validated High-Risk Tool\* * Expected to be discharged from hospital within the next several days Exclusion Criteria: * Primary neurological diagnosis as the reason for ICU admission * Identified by the clinical team as being on the palliative care pathway * Physical activity primarily limited by the acute injury (e.g., major trauma or limb amputation) * Unable to mobilise independently prior to the index hospitalisation requiring ICU admission due to a long-term condition and/or disability * Lack of capacity or inability to provide informed consent * The High-Risk Tool (Walsh et al., 2022) assesses eight domains: recent hospital admissions; multimorbidity (≥4 chronic conditions); polypharmacy (≥4 regular medications); prior mental health disorder; substance misuse history; current antidepressant or antipsychotic therapy; need for assistance with activities of daily living (ADLs); and living alone or fragile social circumstances. Patients meeting ≥3 domains are classified as high risk for post-ICU deterioration and readmission.