Clinical Research Directory
Browse clinical research sites, groups, and studies.
Effects of Frequency Adjustment in Functional Electrical Stimulation on Genioglossus Muscle Activity
Sponsor: Seoul National University Bundang Hospital
Summary
This single-group interventional study investigates the safety and physiologic effects of functional electrical stimulation (FES) applied to the tongue and submental muscles in adults at high risk for sleep apnea. Participants will receive five stimulation frequencies (15, 25, 35, 45, and 75 Hz) in randomized order during a single visit. Ultrasound and tongue pressure (IOPI) measurements, as well as subjective assessments of discomfort and perceived effects, will be conducted before, during, and after stimulation. The primary objective is to evaluate changes in muscle thickness, length, and tongue strength across different stimulation frequencies. Secondary objectives include assessing participant discomfort, safety, and subjective treatment effects.
Key Details
Gender
All
Age Range
19 Years - Any
Study Type
INTERVENTIONAL
Enrollment
28
Start Date
2026-01-06
Completion Date
2026-04
Last Updated
2026-03-12
Healthy Volunteers
Yes
Conditions
Interventions
Functional Electrical Stimulation Device
A functional electrical stimulation device is applied to the submental region using surface adhesive electrodes. Stimulation is delivered at five different frequencies (15, 25, 35, 45, and 75 Hz) in randomized sequence during a single study visit. Each frequency is administered within the same session to evaluate immediate physiologic responses of the tongue muscles. Participants are blinded to the stimulation frequency applied during each condition.
Locations (1)
Seoul National University Bundang Hospital
Gyeonggi-do, Seongnam-si, South Korea