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NOT YET RECRUITING
NCT07467018

Mobile Vehicle-Based Delivery of Lenacapavir PrEP in Los Angeles County

Sponsor: University of California, Los Angeles

View on ClinicalTrials.gov

Summary

This project evaluates the implementation strategy of the delivery of lenacapavir pre-exposure prophylaxis (LEN PrEP) - a newly available long-acting, injectable medication for HIV prevention - via a mobile health van model for people who are unstably housed in Los Angeles County. People who are unhoused or are facing housing instability experience significant barriers to accessing HIV prevention care in traditional clinic settings. In 2022, approximately 13% of newly diagnosed HIV cases in Los Angeles County were experiencing homelessness, a 36% increase over the prior period. We will work with UCLA Health's Homeless Healthcare Collaborative (HHC), which operates mobile health vans staffed by clinicians, social workers, and community health workers, to bring LEN PrEP directly to community settings, such as shelters, encampments, community centers, and transitional housing facilities. This study has three primary aims: 1. Characterize uptake of LEN PrEP among unstably housed people in Los Angeles County receiving health services via HHC's mobile program. 2. Evaluate how many study participants stay on LEN PrEP through 52 weeks. 3. Understand costs, acceptability, and sustainability of the mobile LEN PrEP delivery model.

Official title: Mobile Vehicle-Based Delivery of Lenacapavir PrEP in Los Angeles County (MOVE-LA)

Key Details

Gender

All

Age Range

18 Years - Any

Study Type

OBSERVATIONAL

Enrollment

100

Start Date

2026-04-07

Completion Date

2027-12-31

Last Updated

2026-03-27

Healthy Volunteers

No

Conditions

Interventions

OTHER

Community-based healthcare delivery

This study evaluates the implementation strategy of community-based delivery of HIV biomedical prevention with lenacapavir.

DRUG

Lenacapavir

Mobile, community-based delivery of lenacapavir

Locations (1)

UCLA Health Homeless Healthcare Collaborative

Santa Monica, California, United States