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Focal Radiation Therapy (HDR-Brachytherapy) for the Treatment of Prostate Cancer
Sponsor: Jonsson Comprehensive Cancer Center
Summary
This clinical trial tests the effect of focal radiation therapy, high dose rate-brachytherapy (HDR-BT), in treating patients with prostate cancer. Prostate cancer is the most diagnosed cancer in men and there are many treatments available, including surgery and radiation therapy. Although surgery and radiation therapy improve survival urinary and sexual function can be significantly affected and can be long lasting. HDR-BT, a type of focal radiation therapy also known as internal radiation therapy, uses radioactive material placed directly into or near a tumor to kill tumor cells. Giving HDR-BT may be effective in providing local control while reducing side effects in patients with prostate cancer.
Official title: Phase II Trial of Focal Radiation Therapy in Patients With Prostate Cancer
Key Details
Gender
MALE
Age Range
40 Years - Any
Study Type
INTERVENTIONAL
Enrollment
45
Start Date
2026-04-04
Completion Date
2032-04-04
Last Updated
2026-03-19
Healthy Volunteers
No
Conditions
Interventions
Biopsy Procedure
Undergo tumor biopsy
Biospecimen Collection
Undergo blood sample collection
High-Dose Rate Brachytherapy
Undergo HDR-BT
Multiparametric Magnetic Resonance Imaging
Undergo mpMRI
PSMA PET Scan
Undergo PSMA PET
Questionnaire Administration
Ancillary studies
Locations (1)
UCLA / Jonsson Comprehensive Cancer Center
Los Angeles, California, United States