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NOT YET RECRUITING
NCT07468903
NA

Focal Radiation Therapy (HDR-Brachytherapy) for the Treatment of Prostate Cancer

Sponsor: Jonsson Comprehensive Cancer Center

View on ClinicalTrials.gov

Summary

This clinical trial tests the effect of focal radiation therapy, high dose rate-brachytherapy (HDR-BT), in treating patients with prostate cancer. Prostate cancer is the most diagnosed cancer in men and there are many treatments available, including surgery and radiation therapy. Although surgery and radiation therapy improve survival urinary and sexual function can be significantly affected and can be long lasting. HDR-BT, a type of focal radiation therapy also known as internal radiation therapy, uses radioactive material placed directly into or near a tumor to kill tumor cells. Giving HDR-BT may be effective in providing local control while reducing side effects in patients with prostate cancer.

Official title: Phase II Trial of Focal Radiation Therapy in Patients With Prostate Cancer

Key Details

Gender

MALE

Age Range

40 Years - Any

Study Type

INTERVENTIONAL

Enrollment

45

Start Date

2026-04-04

Completion Date

2032-04-04

Last Updated

2026-03-19

Healthy Volunteers

No

Interventions

PROCEDURE

Biopsy Procedure

Undergo tumor biopsy

PROCEDURE

Biospecimen Collection

Undergo blood sample collection

RADIATION

High-Dose Rate Brachytherapy

Undergo HDR-BT

PROCEDURE

Multiparametric Magnetic Resonance Imaging

Undergo mpMRI

PROCEDURE

PSMA PET Scan

Undergo PSMA PET

OTHER

Questionnaire Administration

Ancillary studies

Locations (1)

UCLA / Jonsson Comprehensive Cancer Center

Los Angeles, California, United States