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Serum Inflammatory Protein Concentration During Dental Treatment
Sponsor: Ohio State University
Summary
The goal of this observational study is to study the molecular markers of stress in blood samples from people who are having periodontal surgery. The main question it aims to answer are: * How do the levels of inflammatory molecules in the blood change during a periodontal surgery? * How are the levels of inflammatory molecules in a person having surgery different from the levels in a person having a nonsurgical procedure? * Participants will be people who are having a periodontal surgery or a nonsurgical periodontal treatment as part of their dental care. Participants will be asked to let the investigator take blood samples from them before, during, and after the procedure is being done. The blood will later be analyzed for substances in the blood that are associated with inflammation.
Official title: Systemic Molecular Markers of Surgical Trauma in Periodontitis/Peri-implantitis Patients
Key Details
Gender
All
Age Range
21 Years - 75 Years
Study Type
OBSERVATIONAL
Enrollment
30
Start Date
2026-02
Completion Date
2027-02
Last Updated
2026-03-16
Healthy Volunteers
No
Conditions
Interventions
Blood samples for inflammatory markers
Blood samples will be obtained before the start of the procedure, the midpoint of the procedure, and the end of the procedure.
periodontal surgery
Periodontal/peri-implant surgical interventions, with or without IV sedation, as based on treatment needs
Periodontal maintenance
Regular cleaning to maintain health after surgical treatment for periodontal disease
Non-surgical deep cleaning
Debridement under local anesthesia, as based on treatment needs
Locations (1)
The Ohio State University Graduate Periodontics Clinic
Columbus, Ohio, United States