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The Effects of High-dose Vitamin B6 on Depression and Anxiety Symptoms
Sponsor: University of Reading
Summary
This clinical trial investigates the effects of Vitamin B6 supplementation on neural inhibition using electroencephalography (EEG), in relation to depression and anxiety symptoms in participants from the general population with a relatively high level of symptoms at baseline. Researchers will compare a placebo group to high-dose Vitamin B6 to test the hypothesis that Vitamin B6 moves the excitation/inhibition balance towards inhibition.
Official title: An EEG Study to Investigate the Effect of High-dose Vitamin B6 Supplementation on Neural Activity in Relation to Depression and Anxiety Symptoms.
Key Details
Gender
All
Age Range
18 Years - 41 Years
Study Type
INTERVENTIONAL
Enrollment
44
Start Date
2026-02
Completion Date
2026-11
Last Updated
2026-03-17
Healthy Volunteers
Yes
Conditions
Interventions
Pyridoxal-5'-Phosphate supplement
100mg PLP in the form of a tablet, taken once a day for 1 week
Placebo Supplementation
Placebo supplement in the form of a capsule.
Locations (1)
Harry Pitt Building
Reading, England, United Kingdom