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Small Bowel Capsule Endoscopy in Lynch Syndrome
Sponsor: Assistance Publique - Hôpitaux de Paris
Summary
The impact of small bowel (SB) capsule endoscopy (CE) on the screening (followed by diagnosis and treatment) of (pre)neoplastic lesions of the small bowel in Lynch syndrome (LS) patients is unknown. The iCARE4Lynch study is a retrospective cohort of patients carrying a pathogenic variant of the DNA mismatch repair gene (MMR) (MLH1, MSH2, MSH6, PMS2, EPCAM) who had had at least one SBCE for screening of small bowel (pre)neoplastic lesions between January 1st 2000 and December 31 2024.
Official title: Small Bowel Capsule Endoscopy for (Pre)Neoplastic Lesion Screening in Patients With Lynch Syndrome
Key Details
Gender
All
Age Range
18 Years - Any
Study Type
OBSERVATIONAL
Enrollment
400
Start Date
2025-06-16
Completion Date
2026-12
Last Updated
2026-03-16
Healthy Volunteers
No
Locations (1)
Center for Digestive Endoscopy, Saint-Antoine Hospital
Paris, France