Clinical Research Directory

Inclusion criteria for children with myopia: * Children aged between 8 and 13 years (inclusive) * Signed informed consent of child and legal guardian * Normal ophthalmic findings except myopia * Cycloplegic spherical equivalent (SE) refraction ≤ -1.0dpt in both eyes * Normal findings in the medical history unless the investigator considers an abnormality to be clinically irrelevant Inclusion criteria for healthy age- and sex-matched controls: * Children aged between 8 and 13 years (inclusive) * Signed informed consent of child and legal guardian * Normal ophthalmic findings * Cycloplegic spherical equivalent (SE) refraction between +0.5dpt and -0.5dpt * Normal findings in the medical history unless the investigator considers an abnormality to be clinically irrelevant Exclusion Criteria: * Intake of stimulating beverages containing xanthine derivatives (tea, coffee, cola-like drinks) 12 hours before the study day * Previous eye abnormalities such as cataract, keratopathy, strabismus, amblyopia, ocular inflammation, trauma, or surgery * History of any disease or syndrome associated with severe myopia such as Marfan syndrome, Stickler syndrome, or retinopathy of prematurity * Non-axial cause of myopia * BCVA less than 20/25 * Intraocular pressure ≥ 21mmHg * Astigmatism ≤ -1.0dpt * Anisometropia ≥ 2dpt * Not able to read letters for visual acuity testing