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Portable VR-based Chromatic Pupilloperimeter for Diagnosis and Monitoring of Traumatic Brain Injury
Sponsor: Sheba Medical Center
Summary
Accurate and non-invasive methods for objectively identifying and monitoring head injuries (such as a concussion) are still an unmet need. It is known that pupil constriction in response to light stimuli can reflect changes in neural activity in the brain and is associated with sleep disturbances. The investigators aim to examine the feasibility of using virtual reality goggles for monitoring traumatic brain injury by analyzing the pupillary response to multifocal chromatic stimuli. The VR device was programmed to present brief, low-intensity light stimuli (without glare), while the headset's camera records the pupil's reaction.
Official title: Development of a Portable VR-based Chromatic Pupilloperimeter for Diagnosis and Monitoring of Traumatic Brain Injury
Key Details
Gender
All
Age Range
18 Years - 67 Years
Study Type
OBSERVATIONAL
Enrollment
150
Start Date
2026-04-01
Completion Date
2027-12-31
Last Updated
2026-04-02
Healthy Volunteers
Yes
Interventions
Virtual Reality pupillometry test
A short (less than 10 minute) chromatic pupilloperimetry test administered via virtual reality (VR) goggles. Participants are exposed to brief, low-intensity chromatic light stimuli within the VR environment, designed to elicit pupillary responses without causing glare. Pupil size is monitored, enabling objective assessment of neural function and potential indicators of head trauma.
Locations (1)
Sheba Medical Center
Tel Litwinsky, Tel Aviv (Gosh Dan), Israel