Clinical Research Directory

Inclusion Criteria: 1. Adults aged between 50 and 79 years 2. Current smokers or ex-smokers quitted for less than 10 years, with a history of cigarette smoking equivalent to at least 20 pack-years Exclusion Criteria: 1. Non-Chinese population 2. Individuals who are not mentally competent to provide informed consent (e.g., those with a history of dementia) 3. Individuals with a known prior diagnosis of lung cancer or detection of lung nodules 4. Individuals with a history of other cancers within the last five years or currently under treatment 5. Individuals who have undergone a CT scan of the thorax in the previous 12 months 6. Individuals who are either unwilling to undergo a chest LDCT scan, or having a condition that prevents them from having a LDCT scan (for example, pregnancy or inability to lie flat on the CT table)