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Local Radiofrequency Ablation Plus External Beam Radiation for the Treatment of Painful Thoracic and Lumbar Spine Tumors
Sponsor: UNC Lineberger Comprehensive Cancer Center
Summary
This study looks at how well a combination of treatments helps reduce pain in people with tumors in the middle and lower back (thoracic and lumbar spine). All participants receive the same treatment, which includes a procedure to stabilize the spine (kyphoplasty), radiofrequency ablation will be with the Osteocool system and radiation therapy. The goal is to see how effective this combined approach is at relieving pain. The purpose of this study is to find out whether combining these three treatments provides better pain relief for patients with thoracic and lumbar spine tumors. This study is for adults who have cancer that has spread to the thoracic or lumbar spine and who report moderate to severe back pain (a pain score of 5 or higher on a 0-10 pain scale).
Official title: Local Radiofrequency Ablation Plus External Beam Radiation for the Treatment of Painful Thoracic and Lumbar Spine Tumors -SPARC
Key Details
Gender
All
Age Range
18 Years - Any
Study Type
OBSERVATIONAL
Enrollment
70
Start Date
2026-03-20
Completion Date
2031-03-01
Last Updated
2026-03-24
Healthy Volunteers
No
Conditions
Interventions
kyphoplasty with Osteocool
Participants will receive kyphoplasty with Osteocool prior to their Standard of Care External Beam Radiotherapy.
Locations (1)
UNC Hospitals
Chapel Hill, North Carolina, United States