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Estimated Risk of Preeclampsia in the First Trimester and Its Association With Subclinical Atherosclerosis and Cardiovascular Risk in Women With Type 1 Diabetes
Sponsor: Institut d'Investigacions Biomèdiques August Pi i Sunyer
Summary
This multicenter observational cohort study aims to evaluate whether estimated first-trimester risk of preeclampsia (PE) is associated with subclinical atherosclerosis, cardiovascular risk profile, and cardiovascular events in women with type 1 diabetes (T1D) at least 3 years after pregnancy. Women with T1D and at least one prior pregnancy with documented first-trimester PE screening will be classified as high or low PE risk according to validated multivariable algorithms. The presence of carotid plaques, cardiometabolic risk factors, and incident cardiovascular events will be assessed during a study visit.
Key Details
Gender
FEMALE
Age Range
18 Years - Any
Study Type
OBSERVATIONAL
Enrollment
1300
Start Date
2026-04-10
Completion Date
2028-04-30
Last Updated
2026-03-18
Healthy Volunteers
No
Locations (2)
Hospital Clínic Barcelona
Barcelona, Barcelona, Spain
Hospital Universitari Mútua Terrassa
Terrassa, Terrassa, Spain