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NOT YET RECRUITING
NCT07479329

Estimated Risk of Preeclampsia in the First Trimester and Its Association With Subclinical Atherosclerosis and Cardiovascular Risk in Women With Type 1 Diabetes

Sponsor: Institut d'Investigacions Biomèdiques August Pi i Sunyer

View on ClinicalTrials.gov

Summary

This multicenter observational cohort study aims to evaluate whether estimated first-trimester risk of preeclampsia (PE) is associated with subclinical atherosclerosis, cardiovascular risk profile, and cardiovascular events in women with type 1 diabetes (T1D) at least 3 years after pregnancy. Women with T1D and at least one prior pregnancy with documented first-trimester PE screening will be classified as high or low PE risk according to validated multivariable algorithms. The presence of carotid plaques, cardiometabolic risk factors, and incident cardiovascular events will be assessed during a study visit.

Key Details

Gender

FEMALE

Age Range

18 Years - Any

Study Type

OBSERVATIONAL

Enrollment

1300

Start Date

2026-04-10

Completion Date

2028-04-30

Last Updated

2026-03-18

Healthy Volunteers

No

Locations (2)

Hospital Clínic Barcelona

Barcelona, Barcelona, Spain

Hospital Universitari Mútua Terrassa

Terrassa, Terrassa, Spain