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Comparison Between Liquid-Based Cytology And Molecular Screening For Detecting Precursor Lesions and Cervical Cancer
Sponsor: Timser SAPI de CV
Summary
This study compares how effective is the molecular screening (a blood test) using Pap smear as reference, that is, a comparison of these tests abilities to detect precursor lesions and cervical cancer among women of an open population
Official title: Study To Compare The Efficacy Of Cervical Cytology With Molecular Screening For Detecting Reactive Cellular Changes In The Cervix In An Open Population
Key Details
Gender
FEMALE
Age Range
18 Years - 85 Years
Study Type
INTERVENTIONAL
Enrollment
558
Start Date
2026-02-03
Completion Date
2026-06
Last Updated
2026-03-18
Healthy Volunteers
Yes
Conditions
Interventions
Physical examination
Physical examination and interview for obtaining a medical record of each participant
Liquid-based cytology
Screening test for cervical precursor lesions and/or cancer. LBC is a procedure in which a cervical smear is examined under the microscope
Molecular screening
The molecular screening detects three human biomarkers associated with cervical precursor lesions and/or cervical cancer. Biomarker detection is done by Western blot and ELISA in human sera
HPV DNA test
HPV DNA detection is performed using a cervical swab
Colposcopy
A diagnostic procedure to visually examine the cervix, vagina, and vulva with a colposcope
Histopathology
Is the definitive diagnosis of cervical precursor lesions and cervical cancer. It is the microscopic study of diseased cells and tissues stained with hematoxylin and eosin
Locations (1)
Consultorio Médico TIMSER
Mexico City, Mexico City, Mexico