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RECRUITING
NCT07480902
NA

Comparison Between Liquid-Based Cytology And Molecular Screening For Detecting Precursor Lesions and Cervical Cancer

Sponsor: Timser SAPI de CV

View on ClinicalTrials.gov

Summary

This study compares how effective is the molecular screening (a blood test) using Pap smear as reference, that is, a comparison of these tests abilities to detect precursor lesions and cervical cancer among women of an open population

Official title: Study To Compare The Efficacy Of Cervical Cytology With Molecular Screening For Detecting Reactive Cellular Changes In The Cervix In An Open Population

Key Details

Gender

FEMALE

Age Range

18 Years - 85 Years

Study Type

INTERVENTIONAL

Enrollment

558

Start Date

2026-02-03

Completion Date

2026-06

Last Updated

2026-03-18

Healthy Volunteers

Yes

Interventions

PROCEDURE

Physical examination

Physical examination and interview for obtaining a medical record of each participant

OTHER

Liquid-based cytology

Screening test for cervical precursor lesions and/or cancer. LBC is a procedure in which a cervical smear is examined under the microscope

OTHER

Molecular screening

The molecular screening detects three human biomarkers associated with cervical precursor lesions and/or cervical cancer. Biomarker detection is done by Western blot and ELISA in human sera

OTHER

HPV DNA test

HPV DNA detection is performed using a cervical swab

DIAGNOSTIC_TEST

Colposcopy

A diagnostic procedure to visually examine the cervix, vagina, and vulva with a colposcope

DIAGNOSTIC_TEST

Histopathology

Is the definitive diagnosis of cervical precursor lesions and cervical cancer. It is the microscopic study of diseased cells and tissues stained with hematoxylin and eosin

Locations (1)

Consultorio Médico TIMSER

Mexico City, Mexico City, Mexico