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ACTIVE NOT RECRUITING
NCT07482007
NA

Oropharyngeal Care With Colostrum, Chlorohexidine and Sodium Bicarbonate in Preventing Ventilator-associated Pneumonia in Preterm Neonates

Sponsor: Tanta University

View on ClinicalTrials.gov

Summary

comparing the effect of oral care with colostrum, chlorohexidine and sodium bicarbonate in prevention of ventilator-associated pneumonia in preterm neonates.

Official title: Comparative Study of Oropharyngeal Care With Colostrum, Chlorohexidine and Sodium Bicarbonate in Preventing Ventilator-associated Pneumonia in Preterm Neonates

Key Details

Gender

All

Age Range

Any - Any

Study Type

INTERVENTIONAL

Enrollment

80

Start Date

2024-04-01

Completion Date

2026-03

Last Updated

2026-03-19

Healthy Volunteers

No

Interventions

OTHER

Oropharyngeal Care with Colostrum

Application of small amounts of expressed maternal colostrum to the oral mucosa of ventilated preterm neonates using sterile swabs every 3-4 hours according to NICU oral care protocol.

DRUG

Chlorhexidine Oral Care

Oropharyngeal care using diluted chlorhexidine solution applied to the oral cavity of ventilated preterm neonates at scheduled intervals according to NICU protocol.

OTHER

Sodium Bicarbonate oral care

Preterm neonates receiving oral care using sodium bicarbonate solution applied to the oral mucosa using sterile swabs.

OTHER

Normal Saline Oral Care

Routine oropharyngeal care using sterile normal saline applied with sterile swabs at regular intervals during mechanical ventilation.

Locations (1)

Neonatal Intensive Care Unit, Tanta University Children's Hospital

Tanta, Egypt