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RECRUITING
NCT07486544
PHASE3

Soaked Pharyngeal Packing Agents in Septoplasty

Sponsor: Assiut University

View on ClinicalTrials.gov

Summary

Postoperative sore throat (POST) is a frequent and distressing complication after general anesthesia with endotracheal intubation, particularly in nasal surgery for example, functional endoscopic sinus surgery, septoplasty, or septo-rhinoplasty, where pharyngeal packing is routine. While pharyngeal packs may reduce blood ingestion, they may exacerbate POST, warranting effective pharmacologic prophylaxis. This study assesses the efficacy of dexamethasone-soaked pharyngeal packs in reducing incidence of POST in patients undergoing elective septoplasty surgeries.

Official title: Comparative Evaluation of Soaked Pharyngeal Packing Agents in Septoplasty Procedure: Impact on Postoperative Outcomes

Key Details

Gender

All

Age Range

18 Years - 65 Years

Study Type

INTERVENTIONAL

Enrollment

90

Start Date

2026-03-20

Completion Date

2026-06-04

Last Updated

2026-03-24

Healthy Volunteers

No

Conditions

Interventions

OTHER

Saline (NaCl 0,9 %) (placebo)

The anesthetist, unaware of group allocation, will place the saline soaked pharyngeal pack under direct visualization following intubation. The pharyngeal pack will be situated in the oropharynx, positioned posterior to the soft palate and in contact with the posterior pharyngeal wall. Placement will be executed with forceps under direct observation, adhering to a standardized protocol to guarantee uniformity across all patients.

DRUG

dexamethasone 8mg

The anesthetist, unaware of group allocation, will place the dexamethasone soaked pharyngeal pack under direct visualization following intubation. The pharyngeal pack will be situated in the oropharynx, positioned posterior to the soft palate and in contact with the posterior pharyngeal wall. Placement will be executed with forceps under direct observation, adhering to a standardized protocol to guarantee uniformity across all patients.

Locations (1)

Assiut University

Asyut, Egypt