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Autologous Whole Blood Therapy in Chronic Idiopathic Urticaria Patients.
Sponsor: Cairo University
Summary
To evaluate the efficacy of Autologous Whole Blood Therapy versus conventional treatment using fourfold dose of antihistamines in Autologus serum skin test (ASST) positive and negative Chronic Idiopathic Urticaria (CIU) patients and suggest its possible mechanism of action.
Official title: Autologous Whole Blood Therapy in Autologous Serum Skin Test (ASST) Positive and Negative Chronic Idiopathic Urticaria Patients, a Clinical and Biochemical Randomized Controlled Trial.
Key Details
Gender
All
Age Range
18 Years - Any
Study Type
INTERVENTIONAL
Enrollment
40
Start Date
2026-04-30
Completion Date
2026-11-30
Last Updated
2026-03-20
Healthy Volunteers
No
Conditions
Interventions
Autologous whole blood therapy
The AWBT test group patients will receive 8 doses of autologous whole blood therapy (AWBT) once weekly. The first dose will be 2.5ml and subsequent doses will be 5ml of venous blood, which will be drawn from any accessible vein under aseptic precautions. The blood will be re-injected immediately by deep intramuscular injection (IM) on alternate gluteal regions.
Desloratadine
All patients will take desloratadine 10 mg at four-fold dose daily
Locations (1)
Faculty of Medicine, Cairo university
Cairo, Cairo Governorate, Egypt