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Effects of the Stimulation Site of tsMS With TMS on Functional Mobility in Individuals With Parkinson's Disease
Sponsor: Universidade Federal de Pernambuco
Summary
This randomized clinical trial aims to compare the effects of two different trans-spinal magnetic stimulation (tsMS) application sites, cervical versus thoracic, when combined with repetitive transcranial magnetic stimulation (rTMS), on functional mobility in individuals with Parkinson's disease (PD). Participants diagnosed with PD will be randomized into two intervention groups (rTMS + cervical tsMS or rTMS + thoracic tsMS) and will undergo 10 treatment sessions. Outcomes will include functional mobility, gait speed, motor function, freeing of gait, balance, quality of life, global perceived improvement and adverse events. The study is expected to identify the most effective tsMS application site to enhance mobility and motor outcomes in PD, contributing to the optimization and standardization of tsMS protocols as an adjunct therapy.
Official title: Effects of the Stimulation Site of Trans-spinal Magnetic Stimulation Combined With Transcranial Magnetic Stimulation on Functional Mobility in Individuals With Parkinson's Disease
Key Details
Gender
All
Age Range
40 Years - Any
Study Type
INTERVENTIONAL
Enrollment
30
Start Date
2026-01-05
Completion Date
2026-12
Last Updated
2026-03-23
Healthy Volunteers
No
Conditions
Interventions
Repetitive Transcranial Magnetic Stimulation
Repetitive transcranial magnetic stimulation applied over the primary motor cortex using standardized stimulation parameters.
Cervical Trans-spinal Magnetic Stimulation
Trans-spinal magnetic stimulation applied at the cervical level using standardized stimulation parameters.
Thoracic Trans-spinal Magnetic Stimulation
Trans-spinal magnetic stimulation applied at the thoracic level using standardized stimulation parameters.
Locations (1)
Universidade Federal de Pernambuco
Recife, Pernambuco, Brazil