Clinical Research Directory

Inclusion Criteria: 1. A history of constipation lasting longer than one year 2. Chronic constipation as defined by the Rome IV criteria 3. Being between the ages of 18 and 55 4. Findings consistent with dyssynergic defecation on anorectal manometry and balloon defecography 5. Exclusion of organic and metabolic causes of chronic constipation Exclusion Criteria: 1. Active bowel disease 2. Presence of an active anal fissure 3. History of major abdominal surgery 4. Presence of a neurological disorder 5. Presence of a serious psychiatric disorder 6. Use of medications that cause constipation