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Woundsome Revascularization in Chronic Limb-Threatening Ischemia
Sponsor: Assiut University
Summary
Chronic limb-threatening ischemia (CLTI) is the most severe form of peripheral artery disease and remains a major health problem. Although the angiosome concept was introduced to guide revascularization by restoring direct blood flow to the affected tissue, its usefulness is limited by anatomical variations, collateral circulation, and wounds involving multiple territories. The emerging "woundsome" concept focuses instead on improving arterial perfusion directly to the wound area, recognizing that both direct revascularization and
Official title: Impact of Woundsome Revascularization on the Outcomes of Endovascular Intervention in Patients With Chronic Limb-Threatening Ischemia
Key Details
Gender
All
Age Range
18 Years - Any
Study Type
INTERVENTIONAL
Enrollment
50
Start Date
2026-04-01
Completion Date
2027-10-01
Last Updated
2026-04-01
Healthy Volunteers
No
Conditions
Interventions
Revascularization by Percutaneous Transluminal Angioplasty
Endovascular revascularization is performed under fluoroscopic guidance using femoral artery access. Balloon angioplasty targets infrapopliteal vessels supplying direct blood flow to the wound. Post-procedure angiography assesses wound perfusion (woundsome), and patients are classified as having successful or unsuccessful woundsome revascularization based on contrast opacification around the wound.
Locations (1)
Vascular and Endovascular surgery department Assiut university
Asyut, Asyut Governorate, Egypt